GCDFP-15

| Catalog Number: | 760-4386    |
| Quantity: | 50 tests |
| Controls: | Breast, Breast Carcinoma |
| Isotypes: | IgG |
| Clone Name: | EP1582Y |
| Species: | Rabbit |
| Localization: | Cytoplasmic |
| Regulatory Status: | IVD |
GCDFP-15 is a 15,000-dalton glycoprotein which is localized in the apocrine metaplastic epithelium lining breast cysts and in apocrine glands in the axilla, vulva, eyelid, and ear canal. Approximately 70% of breast carcinomas stain positive with antibody to GCDFP-15. Colorectal carcinomas, as well as mesotheliomas do not stain with this antibody. Lung adenocarcinoma rarely stains with this antibody.
References
1. Mazoujian G, et al., Am J Dermatopathol. 10(1):28-35, 1988.
2. Ansai S, et al., Am J Dermatopathol. 17(3):249-55, 1995.
3. Mazoujian G, et al., Am J Pathol. 110(2):105-12, 1983.
4. Wich MR, et al., Hum Pathol. 20(3):281-7, 1989.
5. Cohen C, et al., Arch Pathol Lab Med. 117(3):291-4, 1993.
6. Raju U, et al., Mod Pathol. 6(5):516-20, 1993.
7. Bhargava R, et al., Am J Clin Pathol. 127:103-113, 2007.
8. Tornos C, et al., Am J Surg Pathol. 29(11):1482-9, 2005.
9. Takeda Y, et al., Arch Pathol Lab Med. 132(2):239-43, 2008.
10. Liegl B, et al., Histopathology. 50(4):439-47, 2007