Factor XIIIa (AC-1A1)

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Factor XIIIa (AC-1A1)

Factor XIIIa (AC-1A1), dermatofibroma, 100x
Catalog Number:760-4384
Ordering Code:05435692001
Quantity:50 tests
Controls:Dermatofibroma
Isotypes:IgG1
Clone Name:AC-1A1
Species:Mouse
Localization:Cytoplasmic
Regulatory Status:IVD


Factor XIIIa is a blood proenzyme that has been identified in platelets, megakaryocyte, and fibroblast-like mesenchymal or histiocytic cells present in the placenta, uterus, and prostate; it is also present in monocytes and macrophages and dermal dendritic cells. Anti- Factor XIIIa has been found to be useful in differentiating between dermatofibroma (90% (+)), dermatofibrosarcoma protuberans (25%(+)) and desmoplastic malignant melanoma (0%(+)). Factor XIIIa positivity is also seen in capillary hemagioblastoma (100%(+)), hemangioendothelioma (100%(+)), hemangiopericytoma (100%(+)), xanthogranuloma (100%(+)), xanthoma (100(+)), hepatocellular carcinoma (93%(+)), glomus tumor (80%(+)), and meningioma (80%(+)).