E-cadherin (EP700Y)

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E-Cadherin (EP700Y)

E-Cadherin (EP700Y), breast carcinoma, 150x
Catalog Number:760-4440
Ordering Code:05973872001
Quantity:50 tests
Controls:Breast, Lung Adenocarcinoma, Pancreas
Isotypes:IgG
Clone Name:EP700Y
Species:Rabbit
Localization:Membranous
Regulatory Status:IVD


E-Cadherin is an adhesion protein that is expressed in cells of epithelial lineage. Anti-E-Cadherin stains positively in glandular epithelium as well as adenocarcinomas of the lung, G.I. tract, and ovary. It has been useful in distinguishing adenocarcinoma from mesothelioma. Another application involves the differentiation of ductal (which stains positive) vs. lobular cancer of the breast. It has also been shown to be positive in some thyroid carcinomas. Loss of E-Cadherin expression has been suggested as a poor prognostic sign in breast carcinoma and non-small cell lung carcinoma.