CD45 (LCA) (2B11 & PD7/26)

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DIAGNOSTICS F. Hoffmann-La Roche Ltd

CD45 (LCA) (2B11 & PD7/26)

CD45 (LCA)(2B11 & PD7/26), tonsil, 150x
Catalog Number:760-4279
Ordering Code:05269423001
Quantity:50 tests
Controls:Lymph Node, Tonsil
Isotypes:IgG1/K
Clone Name:2B11 & PD7/26
Species:Mouse
Localization:Membranous
Regulatory Status:IVD


Anti-Leukocyte Common Antigen (Anti-LCA) monoclonal antibody is routinely used to aid the differential diagnosis of undifferentiated neoplasms, whenever malignant lymphoma is suspected by the morphological or clinical data. It is a highly specific antibody therefore a positive result is highly indicative of lymphoid or myeloid origin. Certain types of lymphoid neoplasms may lack CD45 (Hodgkin's disease, some T-cell lymphomas and some leukemias) so its absence does not rule out a hematolymphoid tumor. This antibody is expressed almost exclusively by cells of hematopoietic lineage and is present in most benign and malignant lymphocytes, erythrocytes and plasma cell precursors.