VENTANA PMS2 (A16-4) Mouse Monoclonal Primary Antibody

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VENTANA anti-PMS2 (A16-4) Mouse Monoclonal Primary Antibody

For use with VENTANA MMR IHC Panel

VENTANA anti-PMS2 (A16-4) Mouse Monoclonal Primary Antibody, colon cancer, 40x
Catalog Number:790-5094
Ordering Code:07862261001
Quantity:50 tests
Controls:CRC tissue with a PMS2 Clinical Status of Intact or normal colon tissue pre-qualified with VENTANA anti-PMS2 (A16-4) antibody
Isotypes:IgG1
Clone Name:A16-4
Species:Mouse
Localization:Nuclear
Regulatory Status:IVD

The VENTANA MMR IHC Panel is a qualitative immunohistochemistry (IHC) test intended for use in the light microscopic assessment of mismatch repair (MMR) proteins (MLH1, PMS2, MSH2, and MSH6) and BRAF V600E proteins in formalin-fixed, paraffin-embedded colorectal cancer (CRC) tissue sections. The OptiView DAB IHC Detection Kit is used with MLH1, MSH2, MSH6 and BRAF V600E, and the OptiView DAB IHC Detection Kit with OptiView Amplification Kit is used for PMS2 detection. The VENTANA MMR IHC Panel is for use on the VENTANA BenchMark ULTRA instrument. The VENTANA MMR IHC Panel includes VENTANA anti-MLH1 (M1) Mouse Monoclonal Primary Antibody, VENTANA anti-PMS2 (A16-4) Mouse Monoclonal Primary Antibody, VENTANA anti-MSH2 (G219-1129) Mouse Monoclonal Primary Antibody, VENTANA anti-MSH6 (SP93) Rabbit Monoclonal Primary Antibody, and VENTANA anti-BRAF V600E (VE1) Mouse Monoclonal Primary Antibody.

The VENTANA MMR IHC Panel is indicated in patients diagnosed with colorectal cancer (CRC) to detect mismatch repair (MMR) proteins deficiency as an aid in the identification of probable Lynch syndrome and to detect BRAF V600E protein as an aid to differentiate between sporadic CRC and probable Lynch syndrome.

Results from the VENTANA MMR IHC Panel should be interpreted by a qualified pathologist in conjunction with histological examination, relevant clinical information, and proper controls.

The clinical performance of this device to guide treatment of MMR deficient patients has not been established.

Intended for in vitro diagnostic (IVD) use. Prescription Use Only.