CONFIRM anti-Topoisomerase IIa (JS5B4) Rabbit Monoclonal Primary Antibody

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CONFIRM anti-Topoisomerase IIα (JS5B4) Rabbit Monoclonal Primary Antibody

CONFIRM anti-Topoisomerase IIα (JS5B4) Rabbit Monoclonal Primary Antibody, tonsil, 80x
Catalog Number:790-4371
Ordering Code:05479339001
Quantity:50 tests
Controls:Spleen, Tonsil
Clone Name:JS5B4
Species:Rabbit
Localization:Nuclear
Regulatory Status:IVD


This antibody is intended for in vitro diagnostic (IVD) use. Ventana Medical Systems, Inc. CONFIRM anti-Topoisomerase IIα (JS5B4) Rabbit Monoclonal Primary Antibody is designed to qualitatively detect the presence of topoisomerase IIa expressing cells via light microscopy in formalin fixed, paraffin embedded tissue following staining on a Ventana BenchMark XT instrument. During the cell cycle, topoisomerase IIα is expressed in the G1, S, G2, and M phase but is absent in the G0 (quiescent) phase.1 Assessment of the proportion of positive staining cells for topoisomerase IIα may aid in evaluation of the proliferative activity of normal and/or neoplastic tissue.2,3,4 The clinical interpretation of any staining, or the absence of staining, must be complemented by morphological studies and evaluation of proper controls. Evaluation must be made by a qualified pathologist within the context of the patient’s clinical history and other diagnostic tests.