p27Kip1 (SX53G8)

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DIAGNOSTICS F. Hoffmann-La Roche Ltd

p27Kip1 (SX53G8)

p27Kip1 (SX53G8), tonsil, 200x
Catalog Number:760-4268
Ordering Code:05269300001
Quantity:50 tests
Controls:Colon, Non Small Cell Lung Carcinoma
Isotypes:IgG1/K
Clone Name:SX53G8
Species:Mouse
Localization:Cytoplasmic
Regulatory Status:IVD


p27 is a cyclin-dependent kinase inhibitor which regulates progression from G1 to S phase by binding and inhibiting cyclin-dependent kinases. Low p27 expression has been associated with unfavorable prognosis in renal cell carcinoma, colon carcinoma, small breast carcinomas, nonsmall-cell lung carcinoma, hepatocellular carcinoma, multiple myeloma, lymph node metastases in Papillary carcinoma of the Thyroid, and more aggressive phenotype in carcinoma of the cervix.