anti-p53 (Bp53-11) Primary Antibody

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anti-p53 (Bp53-11) Primary Antibody

anti-p53 (Bp53-11) Primary Antibody
Catalog Number:760-2542
Ordering Code:05267102001
Quantity:50 tests
Controls:Colon Adenocarcinoma
Isotypes:IgG2a
Clone Name:Bp-53-11
Species:Mouse
Localization:Nuclear
Regulatory Status:IVD


This antibody is intended for in vitro diagnostic (IVD) use. Ventana Medical Systems, Inc. (Ventana) anti-p53 Primary Antibody (Bp53-11) is a mouse monoclonal antibody directed against both the mutant and wild type of the p53 nuclear phosphoprotein. Very rare normal cells express p53, but alterations in the p53 suppressor gene result in an overproduction of this protein in malignancies. This reagent may be used to aid in the identification of abnormally proliferating cells in neoplastic cell populations. The antibody is intended for qualitative staining in sections of formalin fixed, paraffin embedded tissue on a Ventana automated slide stainer. The clinical interpretation of any staining, or the absence of staining, must be complemented by morphological studies and evaluation of proper controls. Evaluation must be made by a qualified pathologist within the context of the patient’s clinical history and other diagnostic tests. Prescription only.