Myosin, Smooth Muscle (SMMS-1)

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DIAGNOSTICS F. Hoffmann-La Roche Ltd

Myosin, Smooth Muscle (SMMS-1)

Myosin, Smooth Muscle (SMMS-1), appendix, 100x
Catalog Number:760-2704
Ordering Code:05268133001
Quantity:50 tests
Controls:Breast, Intestine
Isotypes:IgG1/K
Clone Name:SMMS-1
Species:Mouse
Localization:Cytoplasmic
Regulatory Status:IVD


Smooth Muscle Myosin, heavy chain (SMMS-1) is a cytoplasmic structural protein that is a major component of the contractile apparatus of the smooth muscle cells. SMMS-1 is also a myoepithelium-associated protein. Anti-SMMS-1 is a mouse monoclonal antibody to smooth muscle myosin, heavy chain that reacts with human visceral and vascular smooth muscle cells. The antibody also reacts with human myoepithelial cells. It is very helpful in distinguishing between benign sclerosing breast lesions and infiltrating carcinomas in difficult cases since it strongly stains the myoepithelial layer in the benign lesions while it is negative in the infiltrating carcinomas.